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Updated: Jun 1, 2026
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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
3-(4-Meth-oxy-phen-yl)pyrido[2,3-b]pyrazine
Cui-Ping Wang1, Jing-Bo Yan, Hai-Jun Chi
1School of Chemical Engineering, University of Science and Technology Liaoning, Anshan, 114051, People's Republic of China.
Summary
This study details the molecular structure of C(14)H(11)N(3)O, revealing a twisted benzene ring. Crystal analysis shows molecules stacking via pi-pi interactions and stabilized by hydrogen bonds.
Area of Science:
- Crystallography
- Molecular Chemistry
Background:
- Understanding molecular interactions is key in materials science.
- Crystal packing influences material properties.
Purpose of the Study:
- To elucidate the crystal structure and intermolecular interactions of C(14)H(11)N(3)O.
- To analyze the role of pi-pi stacking and hydrogen bonding in crystal stabilization.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of intermolecular distances and angles was performed.
Main Results:
- The molecule C(14)H(11)N(3)O exhibits a benzene ring twisted by 14.0(2)° from the fused ring system.
- π-π interactions with centroid-centroid distances of 3.609(1) to 3.735(1) Å form molecular stacks along the b axis.
- Crystal packing is further stabilized by weak intermolecular C-H⋯O and C-H⋯N hydrogen bonds.
Conclusions:
- The study provides detailed structural insights into C(14)H(11)N(3)O.
- The identified intermolecular forces dictate the observed crystal packing and molecular arrangement.
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