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Updated: Jun 1, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
4-Amino-N-(3-meth-oxy-pyrazin-2-yl)benzene-sulfonamide
Abstract:
The overall mol-ecular geometry of the title compound, C(11)H(12)N(4)O(3)S, is bent, with a dihedral angle of 89.24 (5)° between the best planes through the two aromatic rings. Each mol-ecule behaves as a hydrogen-bond donor toward three different mol-ecules, through its amidic and the two aminic H atoms, and it behaves as a hydrogen-bond acceptor from two other mol-ecules via one of its sulfonamidic O atoms. In the crystal, mol-ecules linked by N-H⋯N and N-H⋯O hydrogen bonds form kinked layers parallel to (001), adjacent layers being connected by van der Waals inter-actions.
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