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Updated: Jun 1, 2026
11:45
Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
(2-Chloro-8-meth-oxy-quinolin-3-yl)methanol monohydrate
Summary
The crystal structure of a C(11)H(10)ClNO(2)·H(2)O compound was analyzed. Molecules pack via hydrogen bonds and pi-pi interactions, with a notable short chlorine-oxygen contact observed.
Area of Science:
- Crystallography
- Chemical Physics
Background:
- Understanding molecular interactions is crucial in crystal engineering.
- Planar organic molecules often exhibit unique packing arrangements.
Purpose of the Study:
- To elucidate the crystal structure of the title compound C(11)H(10)ClNO(2)·H(2)O.
- To investigate the intermolecular interactions governing crystal packing.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bonding and π-π interactions was performed.
Main Results:
- The organic molecule within C(11)H(10)ClNO(2)·H(2)O is approximately planar (r.m.s. deviation = 0.074 Å).
- Crystal packing is stabilized by O-H⋯O and O-H⋯N hydrogen bonds.
- Weak C-H⋯π and π-π interactions (centroid-centroid distance = 3.578 Å) contribute to packing.
- A short Cl⋯O contact (3.147 Å) was identified.
Conclusions:
- The crystal structure reveals a well-defined packing motif driven by hydrogen bonding.
- The observed short Cl⋯O contact suggests potential non-covalent interactions influencing crystal stability.
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