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Related Experiment Video

Updated: Jun 1, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
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Ethyl 3-(4-methyl-benzyl-idene)carbazate.

Yu-Feng Li, Wen-Hai Sheng, Fang-Fang Jian

    Acta Crystallographica. Section E, Structure Reports Online
    |May 19, 2011
    PubMed
    Summary

    Two similar molecules of C(11)H(14)N(2)O(2) were identified in the crystal structure. These molecules form hydrogen bonds, creating chains along a specific crystallographic direction.

    Area of Science:

    • Crystallography
    • Molecular structure analysis
    • Supramolecular chemistry

    Background:

    • Understanding molecular conformations and intermolecular interactions is crucial in crystal engineering.
    • Hydrogen bonding plays a significant role in dictating crystal packing and material properties.

    Purpose of the Study:

    • To determine the crystal structure of the title compound, C(11)H(14)N(2)O(2).
    • To investigate the conformational characteristics of the molecules in the asymmetric unit.
    • To analyze the intermolecular interactions, specifically hydrogen bonding, within the crystal lattice.

    Main Methods:

    • Single-crystal X-ray diffraction was employed to elucidate the three-dimensional crystal structure.
    • Analysis of the crystal structure revealed the presence of two unique molecules in the asymmetric unit.

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  • Hydrogen bonding networks and chain formation were identified through crystallographic analysis.

    • Main Results:

    • The asymmetric unit contains two C(11)H(14)N(2)O(2) molecules with closely related conformations.
    • Intermolecular N-H⋯O hydrogen bonds were observed between these molecules.
    • These hydrogen bonds lead to the formation of C(4) chains propagating along the [001] direction.

    Conclusions:

    • The crystal structure of C(11)H(14)N(2)O(2) is characterized by the presence of two similar conformers.
    • The identified hydrogen bonding pattern dictates the supramolecular architecture, forming extended chains.
    • This structural information provides insights into the solid-state behavior and potential applications of the compound.