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Updated: Jun 1, 2026
08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
4-(Carboxy-meth-oxy)anilinium bromide.
1Ordered Matter Science Research Center, Southeast University, Nanjing 210096, People's Republic of China.
Summary
This study details the crystal structure of a hydro-bromide salt, revealing hydrogen bonds that link molecules. These interactions form a unique ladder-like structure within the crystal lattice.
Area of Science:
- Crystallography
- Chemical Physics
Background:
- Understanding the crystal structure of salts is crucial for predicting their physical and chemical properties.
- Hydrogen bonding plays a significant role in molecular self-assembly and material properties.
Purpose of the Study:
- To elucidate the crystal structure of the hydro-bromide salt C(8)H(10)NO(3) (+)·Br(-).
- To identify and characterize the hydrogen bonding interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of intermolecular distances and angles to confirm hydrogen bond formation.
Main Results:
- The crystal structure reveals the positive charge localized on the nitrogen atom of the cation.
- The carboxyl group of the cation is protonated.
- Multiple hydrogen bonds (N-H⋯Br, O-H⋯Br, N-H⋯O) were identified, forming a ladder-like arrangement propagating along the a axis.
Conclusions:
- The specific arrangement of hydrogen bonds dictates the overall crystal architecture.
- The identified crystal structure provides a basis for understanding the salt's behavior and potential applications.
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