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Updated: Jun 1, 2026
11:01
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
N'-Benzyl-idene-furan-2-carbohydrazide
Summary
This study details the crystal structure of a novel organic compound, C(12)H(10)N(2)O(2). The research highlights the molecule's specific dihedral angle and intermolecular hydrogen bonding, revealing its crystal packing arrangement.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Understanding the three-dimensional structure of organic molecules is crucial for predicting their properties.
- Intermolecular forces, such as hydrogen bonds, significantly influence crystal packing and material characteristics.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(12)H(10)N(2)O(2).
- To analyze the dihedral angle between the aromatic and heterocyclic rings.
- To investigate the hydrogen bonding network and its role in crystal formation.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and dihedral angles was performed.
- Hydrogen bonding interactions were identified and characterized.
Main Results:
- The dihedral angle between the benzene and furan rings was determined to be 24.6(2)°.
- Molecules are linked via N-H⋯O hydrogen bonds.
- These hydrogen bonds form C(4) chains that propagate along the [010] direction in the crystal lattice.
Conclusions:
- The study provides a detailed structural characterization of C(12)H(10)N(2)O(2).
- The identified hydrogen bonding motif dictates the supramolecular architecture in the solid state.
- This structural information is valuable for the design of new materials with tailored properties.
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