Methyl 6-de-oxy-6-iodo-α-d-galactoside

Area of Science:

• Crystallography
• Organic Chemistry
• Supramolecular Chemistry

Background:

• Understanding the crystal packing and intermolecular interactions of carbohydrate derivatives is crucial for predicting their solid-state properties.
• Galactosides are important biomolecules with diverse biological functions.

Purpose of the Study:

• To elucidate the crystal structure of the title compound, C(7)H(13)IO(5).
• To analyze the hydrogen bonding network and packing motifs in the crystal lattice.
• To compare the observed structural features with those of related galactoside compounds.

Main Methods:

• Single-crystal X-ray diffraction analysis was employed to determine the molecular and crystal structure.
• Analysis of hydrogen bonding interactions (O-H⋯O) and their role in crystal assembly.
• Identification and characterization of packing motifs (e.g., R(2)(2)(10), C(2)(2)(11)).

Main Results:

• The crystal structure of C(7)H(13)IO(5) was successfully determined.
• Molecules are interconnected via O-H⋯O hydrogen bonds, forming linkages around a screw axis.
• Observed packing motifs are analogous to those found in closely related galactoside compounds.
• The galactoside ring adopts a (1)C(4) chair conformation.

Conclusions:

• The hydrogen bonding network dictates the crystal packing of C(7)H(13)IO(5).
• The structural similarity to related compounds suggests conserved packing principles in this class of molecules.
• The conformational analysis of the galactoside ring provides insights into its preferred spatial arrangement in the solid state.