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Related Concept Videos

Redox Titration: Iodimetry and Iodometry01:23

Redox Titration: Iodimetry and Iodometry

Iodometry and iodimetry are analytical methods used to determine the concentration of oxidizing or reducing agents using iodine. In iodometric titrations, the oxidizing analyte solution is usually acidified and treated with an excess of iodide ions, which generates an equivalent amount of iodine in equilibrium with triiodide. The released iodine is subsequently titrated directly against a standardized reducing agent. As the dilute iodine color becomes pale yellow, a few drops of freshly...
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Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
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Regioselective Formation of Enolates

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Related Experiment Video

Updated: Jun 1, 2026

Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography
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Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography

Published on: December 27, 2024

Neoirietriol.

Hiroki Takahashi, Yoshinori Takahashi, Minoru Suzuki

    Acta Crystallographica. Section E, Structure Reports Online
    |May 19, 2011
    PubMed
    Summary
    This summary is machine-generated.

    A novel bromo-diterpenoid, a neoirieane-type compound, was isolated from Laurencia yonaguniensis. Its complex structure and absolute stereochemistry were elucidated, revealing specific hydrogen bonding patterns.

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    Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography
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    A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
    11:44

    A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

    Published on: January 24, 2016

    Area of Science:

    • Natural Products Chemistry
    • Marine Natural Products
    • Organic Chemistry

    Background:

    • Marine algae, particularly Laurencia species, are known sources of diverse secondary metabolites.
    • Bromo-diterpenoids represent a significant class of compounds with potential biological activities.
    • The specific species Laurencia yonaguniensis is described as 'species inedita', highlighting its novelty.

    Purpose of the Study:

    • To isolate and characterize a novel bromo-diterpenoid from Laurencia yonaguniensis.
    • To determine the complete structure and absolute stereochemistry of the isolated compound.
    • To investigate the structural features, including hydrogen bonding, of this new natural product.

    Main Methods:

    • Isolation of the title compound from the marine alga Laurencia yonaguniensis.
    • Determination of the molecular formula (C(20)H(34)Br(2)O(3)) and systematic name.
    • Elucidation of the absolute stereochemistry using spectroscopic and/or crystallographic methods (details not specified in abstract).

    Main Results:

    • A neoirieane-type bromo-diterpenoid was successfully isolated and identified.
    • The absolute stereochemistry of the compound was established as (1S,4R,5R,7R,10S,11S,14R).
    • The structure was found to exhibit both inter- and intra-molecular O-H⋯O hydrogen bonding.

    Conclusions:

    • The study reports the discovery and structural elucidation of a new bromo-diterpenoid from an unexplored marine alga.
    • The established absolute stereochemistry provides a foundation for understanding structure-activity relationships in this compound class.
    • The observed hydrogen bonding patterns offer insights into the molecule's conformation and potential interactions.