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Updated: Jun 1, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
2-Amino-4-methylpyridinium 2-hy-droxy-3,5-dinitro-benzoate
Ching Kheng Quah1, Madhukar Hemamalini, Hoong-Kun Fun
1X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
Abstract:
In the anion of the title mol-ecular salt, C(6)H(9)N(2) (+)·C(7)H(3)N(2)O(7) (-), the two nitro groups are twisted from the attached benzene ring with dihedral angles of 27.36 (10) and 4.86 (11)°. The anion is stabilized by an intra-molecular O-H⋯O hydrogen bond, which generates an S(6) ring motif. In the crystal, the cations and anions are linked by N-H⋯O and C-H⋯O inter-actions and are further consolidated by C-H⋯π inter-actions, to generate a three-dimensional network. A short O⋯N contact of 2.876 (2) Å also occurs.
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