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Updated: Jun 1, 2026
08:12
A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
2-[(E)-(2,3-Dimethyl-phen-yl)imino-meth-yl]phenol.
Summary
This study details the molecular structure of a novel compound, C(15)H(15)NO. It reveals specific dihedral angles and intramolecular hydrogen bonding, crucial for understanding crystal packing and interactions.
Area of Science:
- Crystallography
- Molecular Chemistry
- Organic Chemistry
Background:
- Understanding the three-dimensional arrangement of atoms in organic molecules is fundamental to predicting their properties and reactivity.
- Salicylaldehyde and aniline derivatives are important building blocks in organic synthesis and medicinal chemistry.
Purpose of the Study:
- To elucidate the crystal structure and intermolecular interactions of the title compound, C(15)H(15)NO.
- To analyze the spatial orientation and bonding characteristics within the molecule.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the precise atomic coordinates and bond lengths.
- Analysis of the crystal structure included identifying hydrogen bonding and van der Waals interactions.
Main Results:
- The crystal structure of C(15)H(15)NO was successfully determined, revealing near-planar aniline and salicylaldehyde moieties.
- A significant dihedral angle of 43.69° was observed between these two units.
- Intramolecular O-H⋯N hydrogen bonding formed an S(6) ring motif, and C-H⋯π interactions were identified.
Conclusions:
- The determined structure provides detailed insights into the solid-state behavior of this compound.
- The identified hydrogen bonding and C-H⋯π interactions are key factors governing the crystal packing and molecular stability.
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As with other organic compounds, alcohols and phenols...
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