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Updated: Jun 1, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
2-({4-[(1H-Imidazol-2-ylsulfanyl)methyl]-2,5-dimethylbenzyl}sulfanyl)-1H-imidazole
Malcolm J Applewhite1, Storm V Potts
1Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa.
Abstract:
The title compound, C(16)H(18)N(4)S(2), was prepared by the substitution reaction of two equivalents of 2-mercaptoimidazole for every bromine substituent of 1,4-bis-(bromo-meth-yl)-2,5-dimethyl-benzene. The mol-ecule is located on a crystallographic centre of inversion and therefore adopts a trans configuration with regards to the orientation of the two sulfur atoms. An inter-molecular N-H⋯N hydrogen bond forms layers of mol-ecules parallel to (03). The dihedral angle between the central and terminal rings is 174.8 (2)°.
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