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Updated: Jun 1, 2026
08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
4-(o-Tolyl-amino)-benzaldehyde.
Summary
The crystal structure of a novel organic compound was determined, revealing a dihedral angle of 49.64° between its aromatic rings. This structure is stabilized by various hydrogen bonds, including N-H⋯O, C-H⋯O, and C-H⋯π interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding the three-dimensional arrangement of atoms in organic molecules is crucial for predicting their properties.
- Hydrogen bonding plays a significant role in stabilizing crystal structures and influencing molecular interactions.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(14)H(13)NO.
- To quantify the dihedral angle between the aromatic rings within the molecule.
- To identify and characterize the hydrogen bonding interactions responsible for crystal lattice stabilization.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of the crystal structure data to measure bond lengths, bond angles, and dihedral angles.
- Identification of intermolecular interactions, specifically hydrogen bonds, using crystallographic software.
Main Results:
- The crystal structure of C(14)H(13)NO was successfully determined.
- A dihedral angle of 49.64(18)° was measured between the two aromatic rings.
- The crystal lattice is stabilized by a network of N-H⋯O, C-H⋯O, and C-H⋯π hydrogen bonds.
Conclusions:
- The study provides detailed structural information for the title organic compound.
- The identified hydrogen bonding patterns offer insights into the supramolecular assembly and stability of the crystal.
- This structural data can serve as a foundation for further investigations into the compound's physical and chemical properties.
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