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Updated: Jun 1, 2026
14:11
Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
5-(Pyridin-4-yl)isophthalic acid
Yong-Fang Zhang1, Qing-Fu Zhang, Juan Jin
1College of Chemistry and Chemical Engineering, Liaocheng University, Shandong 252059, People's Republic of China.
Summary
This study details the crystal structure of a novel compound, C(13)H(9)NO(4). Molecular analysis reveals specific planar arrangements and hydrogen bonding, forming an intricate three-dimensional supramolecular framework.
Area of Science:
- Crystallography
- Supramolecular Chemistry
- Organic Chemistry
Background:
- Understanding molecular interactions is crucial in supramolecular chemistry.
- Crystal structure analysis provides insights into intermolecular forces.
- The compound C(13)H(9)NO(4) was synthesized for structural investigation.
Purpose of the Study:
- To determine the crystal structure of C(13)H(9)NO(4).
- To analyze the molecular geometry and intermolecular interactions.
- To elucidate the formation of the supramolecular framework.
Main Methods:
- Single-crystal X-ray diffraction was employed.
- Analysis of atomic deviations and dihedral angles.
- Identification of hydrogen bonding networks (O-H⋯O, O-H⋯N, C-H⋯O).
Main Results:
- The benzene and carboxyl groups are nearly co-planar.
- A dihedral angle of 31.07° exists between the benzene and pyridine rings.
- A 3D supramolecular framework is formed via hydrogen bonding.
Conclusions:
- The crystal structure of C(13)H(9)NO(4) has been successfully elucidated.
- The compound exhibits specific geometric preferences and intermolecular interactions.
- Hydrogen bonding plays a key role in constructing the observed 3D framework.
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