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Updated: Jun 1, 2026
04:38
Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
Tetra-ethyl 1,1'-(ethane-1,2-di-yl)bis-(2,5-dimethyl-1H-pyrrole-3,4-dicarboxyl-ate)
Summary
This study details the molecular structure of a novel organic compound, C(26)H(36)N(2)O(8). The research highlights the specific arrangement of its linked pyrrole rings and substituent groups.
Area of Science:
- Organic Chemistry
- Crystallography
Background:
- Pyrrole derivatives are important scaffolds in medicinal chemistry and materials science.
- Understanding the precise three-dimensional structure of organic molecules is crucial for predicting their properties and reactivity.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(26)H(36)N(2)O(8).
- To analyze the molecular geometry, including the linkage and dihedral angles between pyrrole rings.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular structure.
- The asymmetric unit was analyzed to identify independent molecules and their conformations.
Main Results:
- The asymmetric unit contains two independent molecules of C(26)H(36)N(2)O(8).
- Each molecule features two pyrrole rings connected by an ethylene bridge (-CH(2)CH(2)-).
- Dihedral angles between the pyrrole rings were measured as 14.5(3)° and 16.4(3)° for the two molecules, indicating a non-planar conformation.
Conclusions:
- The crystal structure of C(26)H(36)N(2)O(8) has been successfully determined.
- The study provides detailed insights into the conformational preferences of this bis-pyrrole derivative.
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