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Updated: Jun 1, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
1,2,4-Trimeth-oxy-dibenzo[b,d]furan-3-ol
Abstract:
The title compound, C(15)H(14)O(5), is a natural product, isolated from Sorbus lanata Syn. Pyrus lanata (D. Don) found in Pakistan. The compound is composed of three spiro-fused rings. The dihedral angle between the mean planes of the benzene rings is 4.81 (13)°. The meth-oxy groups are oriented at dihedral angles of 74.44 (14), 83.0 (2) and 66.3 (2)° with respect to the planes of the benzene rings to which they are attached. The mol-ecule is consolidated by three intra-molecular O-H⋯O and C-H⋯O hydrogen bonds. In the crystal, mol-ecules are linked by inter-molecular O-H⋯O hydrogen bonds, forming infinite chains along the b axis.
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