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Updated: Jun 1, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
Ethyl 2-(3-amino-4-hy-droxy-phen-yl)acetate
Fang Zhang1, Wen-De Liang, Gong-Xing Li
1College of Chemistry & Chemical Engineering, Jishou University, Jishou 416000, People's Republic of China.
Abstract:
The asymmetric unit of the title compound, C(10)H(13)NO(3), contains two crystallographically independent mol-ecules with different conformations of the eth-oxy-carbonyl groups; the terminal C-C-O-C torsion angles in the two mol-ecules are 83.6 (6) and -171.1 (3)°, resulting in twisted and straight chain conformations, respectively. The crystal structure is stabilized by inter-molecular N-H⋯O, O-H⋯N and C-H⋯O hydrogen bonds. Intra-molecular hydrogen bonds occur between the amino N and phenolic O atoms.
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