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Updated: Jun 1, 2026
11:01
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(9H-Carbazol-9-ylmeth-yl)diethyl-amine
Wei-Jin Gu1, Zi-Ting Lin, Bing-Xiang Wang
1Department of Applied Chemistry, Nanjing Normal University, Nanjing 210097, People's Republic of China.
Summary
This study details the crystal structure of C(17)H(20)N(2), revealing two molecules in the asymmetric unit. These molecules self-assemble into pillar structures through edge-to-face pi-pi stacking interactions in the solid state.
Area of Science:
- Crystallography
- Materials Science
- Organic Chemistry
Background:
- Understanding molecular arrangement in crystals is crucial for predicting material properties.
- Supramolecular chemistry explores non-covalent interactions that drive self-assembly.
- C(17)H(20)N(2) is a novel organic compound with potential applications in materials science.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(17)H(20)N(2).
- To investigate the intermolecular interactions governing the solid-state packing.
- To characterize the self-assembly behavior driven by pi-pi stacking.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and intermolecular distances.
- Identification and quantification of pi-pi stacking interactions.
Main Results:
- The asymmetric unit contains two C(17)H(20)N(2) molecules with minor differences in geometry.
- Neighboring molecules form extended pillar structures in the crystal lattice.
- Edge-to-face pi-pi stacking interactions with distances of 3.538(3) and 3.496(3) Å were identified as the primary driving force for self-assembly.
Conclusions:
- The crystal structure of C(17)H(20)N(2) is characterized by the formation of molecular pillars.
- Edge-to-face pi-pi stacking is the dominant intermolecular interaction, dictating the observed supramolecular architecture.
- The findings provide insights into the structure-property relationships of organic crystalline materials.
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