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Related Experiment Video

Updated: Jun 1, 2026

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

2-(Methyl-sulfin-yl)benzamide.

¹College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online

|May 19, 2011

Summary

This summary is machine-generated.

This study details the crystal structure of a novel compound, C(8)H(9)NO(2)S. Molecules self-assemble into a 2D framework via hydrogen bonds, revealing unique structural properties.

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Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

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Published on: January 3, 2018

Area of Science:

Crystallography
Organic Chemistry
Materials Science

Background:

Understanding molecular assembly is crucial for designing new materials.
Hydrogen bonding plays a significant role in crystal engineering.

Purpose of the Study:

To elucidate the crystal structure of C(8)H(9)NO(2)S.
To investigate the intermolecular interactions governing its self-assembly.

Main Methods:

Synthesis of C(8)H(9)NO(2)S via oxidation of 2-(methyl-sulfan-yl)benzamide.
Catalysis using 2,2,6,6-tetra-methyl-piperidyl-1-oxy (TEMPO).
X-ray crystallography for structural determination.

Main Results:

The crystal structure reveals molecules linked by N-H⋯O(amide) hydrogen bonds, forming amide-amide dimers.
These dimers extend into a two-dimensional lamellar framework parallel to the (100) plane via amide-sulfinyl N-H⋯O hydrogen bonds.
A dihedral angle of 25.6(2)° exists between the benzene ring and the amide group.

Conclusions:

The compound C(8)H(9)NO(2)S exhibits a unique 2D lamellar structure driven by specific hydrogen bonding interactions.
The synthetic methodology provides a route to novel sulfur-containing organic compounds.
The observed structural features offer insights into crystal engineering and supramolecular chemistry.