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Pharmacokinetics of consecutive low-dose cisplatin

Y Shimizu

    Oncology Reports
    |May 19, 2011
    PubMed
    Summary

    Consecutive low-dose cisplatin (CLD-CDDP) may offer a better therapeutic index than standard bolus-CDDP for ovarian cancer. CLD-CDDP showed higher drug exposure (AUC) and lower kidney toxicity, suggesting improved anti-tumor effects.

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