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Prognostic values of serum CA19-9 and CEA levels for colorectal cancer
T Nakayama1, M Watanabe, T Teramoto
1KEIO UNIV,SCH MED,DEPT SURG,SHINJUKU KU,TOKYO 160,JAPAN.
Abstract:
CA19-9 and CEA are associated with gastrointestinal malignancy as adhesion molecules. We measured serum CA19-9 and CEA levels in 328 patients with colorectal cancer. Both serum CA19-9 and CEA levels correlated significantly with recurrence and survival, respectively. Serum CA19-9 levels correlated significantly with survival according to Astler-Coller stage and multivariate analysis. Serum CEA levels showed no such correlations, although the combination of CEA with CA19-9 improved the sensitivity for predicting recurrence. Assessment of serum CA19-9 levels is more important than that of CEA in the clinical management of patients with colorectal cancer.
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