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Related Experiment Video

Updated: Jun 1, 2026

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 8, 2024

Interventional management for cancer pain.

Doris K Cope¹, Zirong Zhao

¹Department of Anesthesiology, University of Pittsburgh School of Medicine, UPMC St. Margaret Pain Medicine Center, Pittsburgh, PA 15215, USA. copedk@upmc.edu

Current Pain and Headache Reports

|May 19, 2011

Summary

Interventional pain management offers advanced options for cancer pain when medications are insufficient. Techniques like intrathecal infusions and nerve blocks provide crucial alternatives for patients experiencing severe or treatment-resistant pain.

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Last Updated: Jun 1, 2026

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 8, 2024

Area of Science:

Oncology
Pain Medicine
Interventional Pain Management

Background:

Cancer pain is a significant issue, arising from the disease itself (primary and metastatic) and cancer treatments.
Conventional medication management for cancer pain is frequently inadequate.
Treatment complications can limit effective pain medication dosages.

Purpose of the Study:

To review interventional pain management modalities for cancer pain.
To discuss the current outcomes and data for these interventions.

Main Methods:

Review of commonly employed interventional techniques.
Discussion of intrathecal opioid, local anesthetic, and clonidine infusions.
Exploration of neurolytic nerve and sympathetic ganglion blockade.
Examination of radiofrequency techniques.

Main Results:

Interventional modalities serve as a vital tool when pharmacotherapy fails.
Specific techniques like intrathecal infusions and nerve blocks are detailed.
Current outcome data from medical literature are presented for each technique.

Conclusions:

Interventional pain management provides essential options for refractory cancer pain.
These techniques can improve pain control and patient quality of life.
Further research and data on outcomes are crucial for optimizing treatment.