Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recrystallization can stop nitrosamine formation in ranitidine hydrochloride.

Journal of pharmaceutical sciences·2026
Same author

Stabilization of spray-dried monoclonal antibody formulations with polymeric excipients.

Journal of pharmaceutical sciences·2026
Same author

Enhanced integrin-mediated adhesion and proliferation of Schwann cells using highly aligned, dual-functional fibrous scaffolds.

npj soft matter·2026
Same author

Modeling immune responses to autologous and allogeneic human stem cell-derived islet grafts in vivo.

JCI insight·2026
Same author

Development of a Telehealth-Enabled Portable Optical Endomicroscopy System with Targeted Peptides: A Preclinical Feasibility Study for Cervical Cancer Detection.

Cancers·2026
Same author

Peptide concentration gradients and aligned microfiber topography synergize to speed and direct Schwann cell migration.

Acta biomaterialia·2026

Related Experiment Video

Updated: Jun 1, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Fluorinated copolymer nanoparticles for multimodal imaging applications.

Mark M Bailey1, Christine M Mahoney, Kassibla E Dempah

  • 1Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, Kansas 66047, USA; National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8371, Gaithersburg, Maryland 20899, USA.

Macromolecular Rapid Communications
|May 19, 2011
PubMed
Summary

Researchers developed new fluorinated nanoparticles for enhanced biomedical imaging. These novel materials show promise as magnetic resonance imaging (MRI) contrast agents, with ongoing studies to confirm their effectiveness in vitro and in vivo.

More Related Videos

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
07:41

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Related Experiment Videos

Last Updated: Jun 1, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
07:41

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Nanomaterials offer significant potential for advancing biomedical imaging.
  • Novel contrast agents are crucial for improving the resolution and sensitivity of imaging techniques like MRI.

Purpose of the Study:

  • To synthesize and characterize a novel fluorinated nanoparticle.
  • To evaluate its potential as an MRI contrast agent.

Main Methods:

  • Free radical polymerization was employed for nanoparticle synthesis.
  • Secondary ion mass spectrometry (SIMS) was used for surface analysis.
  • Solid-state Nuclear Magnetic Resonance (NMR) spectroscopy was utilized for structural characterization.

Main Results:

  • The synthesized nanoparticles possess fluorinated and nitrogen-containing surface groups.
  • Solid-state NMR confirmed the presence of two distinct fluorine resonances, consistent with the fluorinated monomer structure.

Conclusions:

  • The novel fluorinated nanoparticles are successfully synthesized and characterized.
  • These nanoparticles demonstrate potential for use as MRI contrast agents.
  • Further in vitro and in vivo evaluations are underway to assess their performance.