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Effects of REM sleep deprivation of ACTH-induced yawning
L L Lobo1, B G Neumann, D S Eidman
1Department of Psychobiology, Escola Paulista de Medicina, São Paulo, Brazil.
Pharmacology
|January 1, 1990
Abstract:
Central administration of ACTH in rats induces yawning and stretching. In order to study the effects of REM sleep deprivation on ACTH-induced yawning, the peptide was injected immediately after the REM sleep deprivation period or 24 h later. REM sleep deprivation impaired ACTH-induced yawning, but after a 24-hour recovery period, rats displayed a number of yawns similar to those in control animals. Implications for an involvement of dopaminergic and mainly cholinergic systems are discussed.