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Cognitive screening in community-dwelling elders: performance on the clock-in-the-box
Jennifer G Chester1, Laura J Grande, William P Milberg
1Albert Einstein College of Medicine, Bronx, NY, USA.
The American Journal of Medicine
|May 20, 2011
Summary
The Clock-in-the-Box is a rapid cognitive screening tool that effectively correlates with established cognitive and physical function assessments in older adults. This 2-minute test shows promise for evaluating cognitive health in community-dwelling seniors.
Area of Science:
- Gerontology
- Cognitive Science
- Neurology
Background:
- The Clock-in-the-Box is a novel, rapid 2-minute cognitive screening tool designed for quick assessment.
- Existing cognitive screening tools like the Mini-Mental State Exam (MMSE) require more time for administration.
- Evaluating new screening tools is crucial for efficient and effective cognitive health assessment in older populations.
Purpose of the Study:
- To compare the Clock-in-the-Box's performance against the Mini-Mental State Exam (MMSE) and comprehensive neuropsychological tests.
- To establish normative values for Clock-in-the-Box scores based on age and educational background.
- To investigate the association between Clock-in-the-Box scores and physical functional measures in older adults.
Main Methods:
- A prospective, longitudinal study involving 798 community-dwelling older adults in the Boston area.
- Participants underwent in-home assessments including the Clock-in-the-Box, MMSE, Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), and Short Physical Performance Battery (SPPB).
- Statistical analyses included Spearman correlations and analyses of variance to assess relationships between cognitive and functional measures.
Main Results:
- Clock-in-the-Box performance showed significant correlations with the MMSE (r=0.49) and various neuropsychological tests (r=0.37-0.50).
- Higher Clock-in-the-Box scores were significantly associated with better independent function, indicated by fewer difficulties in ADL and IADL.
- Elevated Clock-in-the-Box scores also correlated positively with higher scores on the SPPB, suggesting a link with better physical performance.
Conclusions:
- The Clock-in-the-Box is a valid and brief cognitive screening tool for older adults.
- Its scores correlate well with established cognitive assessments and measures of both independent and physical functioning.
- The Clock-in-the-Box offers a time-efficient method for cognitive screening in community-dwelling older populations.

