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Related Experiment Video

Updated: Jun 1, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

Acute necrotizing sinusitis caused by Staphylococcus lugdunensis.

Philippa C Matthews¹, Rajeka Lazarus, Andrew Protheroe

¹Department of Microbiology and Infectious Diseases, John Radcliffe Hospital, Oxford Radcliffe Hospitals NHS Trust, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. p.matthews@doctors.org.uk

Journal of Clinical Microbiology

|May 20, 2011

Summary

This summary is machine-generated.

Staphylococcus lugdunensis, typically linked to inguinal infections, is now identified as a cause of bacterial sinusitis. This finding suggests its potential role as an upper airway commensal, capable of causing severe tissue damage.

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Last Updated: Jun 1, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

Area of Science:

Microbiology
Infectious Diseases
Otolaryngology

Background:

Staphylococcus lugdunensis is primarily known for causing infections in the inguinal region.
Its role in upper respiratory tract infections has not been extensively studied.

Observation:

This study reports a case of bacterial sinusitis caused by Staphylococcus lugdunensis.
The patient presented with severe necrotic sinusitis.

Findings:

Staphylococcus lugdunensis can be a causative agent of bacterial sinusitis.
The observed pathology was severe, with significant necrosis.
This suggests Staphylococcus lugdunensis may act as a commensal in the upper airways, with pathogenic potential.

Implications:

Highlights a potential new niche for Staphylococcus lugdunensis as an upper airway commensal.
The organism's capacity for destructive pathology mimics that of Staphylococcus aureus.
This finding may broaden the differential diagnosis for bacterial sinusitis and necessitate further investigation into S. lugdunensis upper airway colonization.