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Updated: Jun 1, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Novel approach to mitral valve repair in childhood dilated cardiomyopathy
P Myers1, M Beghetti, M Cikirikcioglu
1Division of Cardiovascular Surgery, Geneva University Hospital, Geneva, Switzerland. patrick.myers@hcuge.ch
Insights
This study shows a biodegradable annuloplasty ring successfully repaired mitral valve regurgitation in a child with dilated cardiomyopathy. This novel approach offers a promising solution for pediatric heart failure management.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Biomaterials Science
Background:
- Dilated cardiomyopathy in children often leads to mitral regurgitation.
- Current annuloplasty options for pediatric patients are limited.
- Successful mitral valve repair improves symptoms in adult heart failure patients.
Observation:
- A 21-month-old child presented with heart failure due to dilated cardiomyopathy and severe mitral regurgitation.
- Echocardiography revealed dilated left heart cavities, a dilated annulus, and moderate systolic dysfunction.
- The mitral valve was repaired using a 16 mm Bioring Kalangos biodegradable annuloplasty ring.
Findings:
- The child experienced rapid recovery, extubation within 3 hours, and discharge on postoperative day 5.
- Post-procedure, the patient had trivial mitral regurgitation and a 5 mmHg transvalvular gradient.
- At 12 months, the patient remained in NYHA class I with trivial mitral regurgitation.
Implications:
- This is the first report of using a biodegradable annuloplasty ring in a child with dilated cardiomyopathy and mitral regurgitation.
- The biodegradable ring shows potential for durable mitral annulus remodeling and growth with the pediatric patient.
- This technique may offer a new therapeutic avenue for pediatric heart failure management.
Abstract:
Evidence is mounting that mitral valve repair can improve symptoms in adults with dilated cardiomyopathy. Data is currently lacking for children with dilated cardiomyopathy and options for annuloplasty are limited in children. We report on the successful management of a 21 month-old child in heart failure from dilated cardiomyopathy and severe mitral regurgitation. The echocardiogram showed severely dilated left heart cavities, severe mitral regurgitation from a dilated annulus (23 mm, Z-score 1.74) with discrete anterior leaflet tethering, and moderate systolic dysfunction. The mitral valve was repaired using a 16 mm Bioring Kalangos biodegradable annuloplasty ring. The patient was extubated on the third postoperative hour and discharged on the fifth postoperative day with trivial mitral regurgitation and a 5 mmHg mean transvalvular gradient. At 12 months, the patient is in NYHA class I and presents trivial central mitral regurgitation without any transmitral gradient. This represents the first report in successfully managing a child with dilated cardiomyopathy with mitral regurgitation using a novel biodegradable annuloplasty ring, which has the potential to durably remodel the mitral annulus and grow with the patient.
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