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Updated: Jun 1, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
A UNIFIED FRAMEWORK FOR ESTIMATING DIFFUSION TENSORS OF ANY ORDER WITH SYMMETRIC POSITIVE-DEFINITE CONSTRAINTS
Angelos Barmpoutis1, Baba C Vemuri
1The University of Florida, Department of Computer and Information Science and Engineering, Gainesville, Florida 32611.
Abstract:
Cartesian tensors of various orders have been employed for either modeling the diffusivity or the orientation distribution function in Diffusion-Weighted MRI datasets. In both cases, the estimated tensors have to be positive-definite since they model positive-valued functions. In this paper we present a novel unified framework for estimating positive-definite tensors of any order, in contrast to the existing methods in literature, which are either order-specific or fail to handle the positive-definite property. The proposed framework employs a homogeneous polynomial parametrization that covers the full space of any order positive-definite tensors and explicitly imposes the positive-definite constraint on the estimated tensors. We show that this parametrization leads to a linear system that is solved using the non-negative least squares technique. The framework is demonstrated using synthetic and real data from an excised rat hippocampus.
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