Related Experiment Video
Updated: Jun 1, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
How many prognostically significant grades of prostate carcinoma are there?
1TEXAS A&M UNIV,SCH MED,SCOTT & WHITE MEM HOSP,DEPT PATHOL,TEMPLE,TX 76508. TEXAS A&M UNIV,SCH MED,SCOTT & WHITE MEM HOSP,DEPT BIOSTAT,TEMPLE,TX 76508. TEXAS A&M UNIV,SCH MED,VET ADM MED CTR,DEPT PATHOL,TEMPLE,TX 76508. BAYLOR UNIV,SCH MED,HOUSTON,TX 77030. JR COLL,DEPT ALLIED HLTH,TEMPLE,TX. TEXAS A&M UNIV,SCH MED,VET ADM MED CTR,TUMOR REGISTRAR,TEMPLE,TX 76508.
Abstract:
Carcinoma of the prostate (CAP) is often graded as well, moderately or poorly differentiated. We identified 74 well differentiated stage A1 CAP, 58 stage D1 CAP with moderately differentiated metastases, 107 moderately differentiated stage D2 CAP, and 53 poorly differentiated stage D2 CAP and divided each group into 3, 4 or 5 histological patterns. We found that each histological pattern within well, moderately and poorly differentiated prostate carcinoma had similar survival rates. These observations suggest that, using Light microscopy, 3 prognostically significant grades of CAP can be identified - well, moderately and poorly differentiated.
