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Related Experiment Video

Updated: Jun 1, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
04:23

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Published on: April 19, 2022

Primary hepatic carcinoid tumor.

Y Une1, Y Li, K Uemura

  • 1KANAZAWA MED COLL,DEPT PATHOL,KANAZAWA,ISHIKAWA,JAPAN.

Oncology Reports
|May 20, 2011
PubMed
Summary

This case study details a rare primary hepatic carcinoid tumor diagnosed via fine needle biopsy and successfully treated with liver surgery. The patient, presenting with fatigue, lacked typical endocrine symptoms, highlighting diagnostic challenges.

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Area of Science:

  • Hepatobiliary Medicine
  • Surgical Oncology
  • Gastroenterology

Background:

  • Primary hepatic carcinoid tumors are exceptionally rare, often presenting without characteristic endocrine symptoms.
  • Diagnosis can be challenging due to nonspecific symptoms and the tumor's unusual location.
  • Carcinoid tumors originate from neuroendocrine cells and can occur in various organs.

Purpose of the Study:

  • To report a unique case of primary hepatic carcinoid tumor.
  • To describe the diagnostic process, including fine needle biopsy findings.
  • To review surgical management and outcomes for this rare condition.

Main Methods:

  • A case of primary hepatic carcinoid tumor was investigated.
  • Diagnosis was confirmed using fine needle biopsy with Grimelius staining and chromogranin A immunoreactivity.

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Last Updated: Jun 1, 2026

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  • The patient underwent left hepatic trisegmentectomy for treatment.
  • Literature review of previously reported primary hepatic carcinoid tumors was conducted.
  • Main Results:

    • A primary hepatic carcinoid tumor was diagnosed in a patient presenting with generalized fatigue.
    • Biopsy revealed Grimelius-stained, chromogranin A-positive cells, with tumor cells showing argyrophilia.
    • No other primary tumor sites were identified pre- or intraoperatively.
    • Successful surgical resection was achieved via left hepatic trisegmentectomy.

    Conclusions:

    • Primary hepatic carcinoid tumors are rare and can present atypically without endocrine symptoms.
    • Fine needle biopsy is crucial for diagnosing hepatic carcinoid tumors.
    • Surgical resection, such as trisegmentectomy, offers a successful treatment option for localized primary hepatic carcinoid tumors.