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Related Concept Videos

Interpersonal Psychotherapy01:25

Interpersonal Psychotherapy

Interpersonal psychotherapy (IPT) is a structured, time-limited therapeutic approach initially developed to treat depression. It integrates key concepts from psychodynamic, humanistic, and cognitive-behavioral therapies, making it a uniquely eclectic framework. The therapy is rooted in the interpersonal theories of Adolph Meyer and Harry Stack Sullivan, as well as John Bowlby's attachment theory, and focuses on the interplay between interpersonal relationships and emotional well-being.
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Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...

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Related Experiment Video

Updated: Jun 1, 2026

Porcine Normothermic Isolated Liver Perfusion
07:32

Porcine Normothermic Isolated Liver Perfusion

Published on: June 9, 2023

Intraperitoneal hyperthermic perfusion (IPHP).

M Deraco1, M Vaglini, M Santinami

  • 1IST NAZL STUDIO & CURA TUMORI,ANAESTHESIOL & INTENS CARE UNIT,I-20133 MILAN,ITALY. IST NAZL STUDIO & CURA TUMORI,DIV GYNAECOL ONCOL,I-20133 MILAN,ITALY.

Oncology Reports
|May 20, 2011
PubMed
Summary
This summary is machine-generated.

Intraperitoneal hyperthermic perfusion (IPHP) using CDDP and MMC offers a viable treatment for peritoneal carcinomatosis. This study found IPHP comparable to extensive abdominal surgery regarding complications and toxicity.

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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Published on: July 31, 2016

Related Experiment Videos

Last Updated: Jun 1, 2026

Porcine Normothermic Isolated Liver Perfusion
07:32

Porcine Normothermic Isolated Liver Perfusion

Published on: June 9, 2023

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
09:02

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Published on: July 31, 2016

Area of Science:

  • Oncology
  • Surgical Oncology
  • Pharmacology

Background:

  • Peritoneal carcinomatosis presents a significant challenge in cancer treatment.
  • Intraperitoneal hyperthermic perfusion (IPHP) is an emerging therapeutic approach.

Purpose of the Study:

  • To evaluate the clinical introduction and outcomes of IPHP with CDDP and MMC for peritoneal carcinomatosis.
  • To assess the toxicity and complication rates associated with IPHP.

Main Methods:

  • Twenty-six patients with peritoneal carcinomatosis underwent surgical treatment combined with IPHP.
  • IPHP solution contained cisplatin (CDDP) at 25 mg/m(2)/l and mitomycin C (MMC) at 3.3 mg/m(2)/l.
  • Peritoneal carcinomatosis was staged using the Japanese classification (P1-P3).

Main Results:

  • Creatinine and amylase levels were the primary indicators of biological toxicity.
  • The surgical complication rate, including two duodenal fistulas, was comparable to extensive abdominal surgery.
  • Patient outcomes were assessed in relation to carcinomatosis stage.

Conclusions:

  • IPHP with CDDP and MMC is a clinically feasible treatment for peritoneal carcinomatosis.
  • The procedure demonstrates an acceptable safety profile regarding toxicity and surgical complications.
  • Further research may explore optimizing IPHP protocols for improved patient outcomes.