Related Experiment Video
Updated: Jun 1, 2026

Flow Cytometric Detection of Newly-formed Breast Cancer Stem Cell-like Cells After Apoptosis Reversal
Published on: January 26, 2019
Identification of spontaneous programmed cell death during development of human breast cancer
1SHANGHAI MED UNIV,CANC HOSP,DEPT PATHOL,SHANGHAI 200032,PEOPLES R CHINA. UNIV MARYLAND,CTR CANC,BALTIMORE,MD 21201.
Abstract:
Breast tumorigenesis proceeds through an accumulation of specific genetic alteration. Breast malignant transformation is dependent not only on the rate of cell production but also on apoptosis, a genetically programmed process of autonomous cell death. We investigated whether breast tumorigenesis involves an altered susceptibility to apoptosis by examining normal breast epithelium and breast cancer samples. We found there is a significant inhibition of spontaneous apoptosis in breast cancer cells compared with normal breast epithelium. The inhibition of apoptosis in breast cancer may contribute to neoplastic transformation.
More Related Videos
19:44Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
Published on: May 30, 2012
15:53Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells
Published on: August 21, 2013
Related Concept Videos
Overview of Cell Death
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the 20th century...
The Intrinsic Apoptotic Pathway
Cellular Injury V: Apoptosis and Autophagy