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Published on: November 8, 2024
Moderate alcohol consumption and the risk of mortality
1Department of Sociology, Virginia Tech, Blacksburg, VA 24061, USA. fullertd@vt.edu
Abstract:
There has been a growing consensus that moderate consumption of alcohol is associated with a lower risk of mortality and that this association is probably causal. However, a recent review article has raised a serious challenge to this consensus. In short, it determined that most prior research in this area committed serious misclassification errors; furthermore, among those studies that were free of these misclassification errors, no support for a protective role of alcohol consumption was found. This article reexamines the issue using prospective data for more than 124,000 persons interviewed in the U.S. National Health Interview Surveys of 1997 through 2000 with mortality follow-up through 2002 using the Linked Mortality File. The study involves about 488,000 person-years. Controlling for a variety of covariates, this study finds that compared with nondrinkers, those who consume a moderate amount of alcohol have lower all-cause and CHD mortality. The fact that the current study has taken care to avoid the pitfalls of some earlier studies and still finds that those who consume a moderate amount of alcohol have lower all-cause mortality and CHD mortality lends credence to the argument that the relationship is causal.
Insights
Moderate alcohol consumption is linked to lower mortality risk, including from coronary heart disease (CHD). This study, avoiding prior errors, supports a causal relationship between moderate drinking and reduced all-cause mortality.
Area of Science:
- Epidemiology
- Public Health
- Cardiovascular Disease Research
Background:
- A prevailing view suggested moderate alcohol intake lowers mortality risk, likely causally.
- Recent reviews questioned this, citing misclassification errors in prior studies and lack of evidence in corrected analyses.
Purpose of the Study:
- To re-evaluate the association between moderate alcohol consumption and mortality.
- To address potential misclassification errors identified in previous research.
Main Methods:
- Prospective cohort study using U.S. National Health Interview Survey data (1997-2000).
- Included over 124,000 participants with mortality follow-up through 2002 (488,000 person-years).
- Controlled for various covariates to minimize confounding factors.
Main Results:
- Moderate alcohol consumption was associated with reduced all-cause mortality.
- Moderate alcohol consumption was also linked to lower coronary heart disease (CHD) mortality.
- Findings persisted after accounting for potential errors in prior studies.
Conclusions:
- This study provides credible evidence supporting a causal link between moderate alcohol consumption and lower all-cause and CHD mortality.
- The findings suggest that the protective association is not solely due to methodological flaws in previous research.
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