Sleep disorders and fibromyalgia.
Suely Roizenblatt1, Nilton Salles Rosa Neto, Sergio Tufik
1Departamento de Psicobiologia, Universidade Federal de São Paulo, Avenida Angélica 1996, Andar 1, São Paulo 01228-200, Brazil. suelyroi@gmail.com
Current Pain and Headache Reports
|May 20, 2011
Summary
Sleep disturbances are key in fibromyalgia, impacting diagnosis and treatment. Therapies like cognitive-behavioral therapy and medications such as sodium oxybate show promise for improving sleep quality in fibromyalgia patients.
Area of Science:
- Rheumatology
- Sleep Medicine
- Clinical Pharmacology
Background:
- Disordered sleep is a hallmark symptom of fibromyalgia, influencing diagnostic criteria and patient quality of life.
- Primary sleep disorders like obstructive sleep apnea and restless leg syndrome can coexist with fibromyalgia.
- Genetic and environmental factors may link fibromyalgia and other sleep disorders.
Purpose of the Study:
- To review the role of sleep disturbances in fibromyalgia.
- To discuss diagnostic approaches for sleep disorders in fibromyalgia.
- To evaluate current and emerging treatments for sleep problems in fibromyalgia.
Main Methods:
- Literature review of diagnostic criteria, sleep studies, and treatment options for fibromyalgia-related sleep disturbances.
- Analysis of non-pharmacological interventions including sleep hygiene and cognitive-behavioral therapy.
- Evaluation of pharmacological treatments, including antidepressants and novel agents like sodium oxybate.
Main Results:
- Polysomnography can identify primary sleep disorders in fibromyalgia patients.
- Sleep hygiene and cognitive-behavioral therapy show positive outcomes for sleep disturbance.
- Amitriptyline is effective for sleep disturbances; sodium oxybate is a new option for sleep management.
Conclusions:
- Sleep disturbances are integral to fibromyalgia, necessitating thorough evaluation and tailored management.
- A multimodal approach combining non-pharmacological and pharmacological strategies is crucial for addressing sleep issues in fibromyalgia.
- Emerging treatments offer new hope for improving sleep and overall well-being in fibromyalgia patients.
More Related Videos
05:59High-Throughput Small Molecule Drug Screening For Age-Related Sleep Disorders Using Drosophila melanogaster
Published on: October 20, 2023
05:34Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
Published on: August 18, 2023
Related Concept Videos
01:24Sleep-Wake Cycles
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
01:17Sedatives and Hypnotics Drugs: Miscellaneous Agents
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
01:07Narcolepsy
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
01:27Insomnia
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
Multiple factors contribute...
01:19Management of Insomnia
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
01:15REM Sleep Behavior Disorder
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...