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Updated: Jun 1, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
Published on: December 20, 2024
[Nonoperative management of spontaneous splenic rupture in infectious mononucleosis]
Andrzej B Szczepanik1, Sławomir Gajda, Anna M Szczepanik
1Instytut Hematologii i Transfuzjologii w Warszawie, Klinika Chirurgii Ogólnej i Hematologicznej. chirurg@ihit.waw.pl
Unlabelled:
Spontaneous splenic rupture is a rare complication of infectious mononucleosis observed in 0.1-0.5% of patients with this condition. Mandatory mode of management in hemodynamically stable patients is nonoperative treatment. We report the case of a 19-year old man with splenic rupture, during the course of serological and hematological confirmed infectious mononucleosis, with no history of trauma. Parenchymal and subcapsular splenic hematomas and presence of blood in vesico-rectal recess was demonstrated. Circulatory and respiratory findings and blood cell count were stable. Nonoperative management was instituted which comprised monitoring of valid vital signs, serial USG and tomography scans and vital activity limitation. Imaging radiological investigations demonstrated disappearance of observed abnormalities on post admission day 20. The patient was discharged from the hospital in good general condition.
Conclusion:
Nonoperative management can be a safe alternative to splenectomy in hemodynamically stable patient with spontaneous rupture of the spleen.
Insights
Spontaneous splenic rupture, a rare infectious mononucleosis complication, can be safely managed nonoperatively in stable patients. This case highlights successful conservative treatment, avoiding splenectomy.
Area of Science:
- Internal Medicine
- Gastroenterology
- Emergency Medicine
Background:
- Spontaneous splenic rupture is a rare but serious complication of infectious mononucleosis (IM).
- Nonoperative management is the standard for hemodynamically stable patients with splenic rupture.
- Infectious mononucleosis affects 0.1-0.5% of patients, with splenic rupture being a rare sequela.
Observation:
- A 19-year-old male presented with spontaneous splenic rupture during confirmed infectious mononucleosis without trauma.
- Imaging revealed splenic hematomas and hemoperitoneum; however, the patient remained hemodynamically stable.
- Conservative management included vital sign monitoring, serial imaging, and activity limitation.
Findings:
- Serial imaging demonstrated complete resolution of splenic hematomas and hemoperitoneum by day 20.
- The patient's vital signs and blood cell counts remained stable throughout hospitalization.
- The patient was discharged in good general condition, indicating successful nonoperative treatment.
Implications:
- Nonoperative management is a viable and safe alternative to splenectomy for hemodynamically stable patients with spontaneous splenic rupture.
- This case supports conservative treatment strategies for splenic rupture associated with infectious mononucleosis.
- Early recognition and appropriate monitoring can lead to favorable outcomes in spontaneous splenic rupture.
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