Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein.
Redox Reactions01:24

Redox Reactions

Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Artificial Intelligence on Polyp Size and Surveillance Colonoscopy: A Phantom Study.

Cureus·2024
Same author

When to feed after percutaneous endoscopic gastrostomy: A systematic review and meta-analysis of randomized controlled trials.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition·2024
Same author

Overlapping Hepatotoxicity and Colitis Associated with Immune Checkpoint Inhibitors.

Journal of community hospital internal medicine perspectives·2023
Same author

EUS-guided <i>versus</i> percutaneous liver biopsy: A prospective randomized clinical trial.

Endoscopic ultrasound·2023
Same author

Respiratory Syncytial Virus Associated Hepatitis in Pregnancy.

Cureus·2022
Same author

International external validation of a stratification tool to identify branch-duct intraductal papillary mucinous neoplasms at lowest risk of progression.

United European gastroenterology journal·2022
Same journal

Proton-Gated Torsional Spring for Molecular Energy Storage.

Journal of the American Chemical Society·2026
Same journal

Topologically Programmed Dual-Channel Covalent Organic Frameworks Decouple Gas and Ion Fluxes for Acidic CO<sub>2</sub> Electroreduction.

Journal of the American Chemical Society·2026
Same journal

Plasmonic Re-Excitation Enables Superoxide-Mediated Ethane Conversion to Acetic Acid under Visible Light.

Journal of the American Chemical Society·2026
Same journal

Photocatalytic Controlled Halodefluorination of Perfluoroalkyl Compounds Using <i>N</i>-Arylphenothiazines.

Journal of the American Chemical Society·2026
Same journal

Photoinduced Disproportionation Enables Oxidative Addition of Aryl Iodides at a Gallium(I) Center.

Journal of the American Chemical Society·2026
Same journal

Biocatalytic C3 β-<i>O</i>-Glycosylation of Triterpenes and Sterols to Synthesize Natural and Unnatural Saponins.

Journal of the American Chemical Society·2026
See all related articles

Related Experiment Video

Updated: Jun 1, 2026

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
07:11

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

Published on: September 28, 2022

Redox-switchable surface for controlling peptide structure.

Brian M Lamb1, Muhammad N Yousaf

  • 1Department of Chemistry, Carolina Center for Cancer Nanotechnology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

Journal of the American Chemical Society
|May 21, 2011
PubMed
Summary
This summary is machine-generated.

Researchers developed a new switchable material using orthogonal click chemistry. This redox-active surface chemistry controls cell adhesion and migration for smart biomaterials.

More Related Videos

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture
09:37

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture

Published on: May 2, 2019

Related Experiment Videos

Last Updated: Jun 1, 2026

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
07:11

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

Published on: September 28, 2022

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture
09:37

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture

Published on: May 2, 2019

Area of Science:

  • Surface Chemistry
  • Biomaterials Science
  • Chemical Biology

Background:

  • Developing switchable materials is crucial for advanced applications.
  • Existing methods for modulating surface properties often lack biocompatibility or real-time control.
  • Understanding dynamic cell adhesion requires adaptable surface chemistries.

Purpose of the Study:

  • To present a general surface chemistry strategy for creating novel switchable materials.
  • To demonstrate a biocompatible, in situ method for modulating molecular interactions on surfaces.
  • To enable real-time studies of dynamic cell adhesion and migration.

Main Methods:

  • Utilized two orthogonal "click" reactions: Huisgen cycloaddition and oxime chemistry.
  • Incorporated a redox-active oxime linkage for switchable functionality.
  • Developed a surface chemistry to modulate cell-adhesive peptide affinity to integrin receptors.

Main Results:

  • Successfully created a switchable surface chemistry strategy.
  • Demonstrated real-time modulation of cell adhesion and migration.
  • Showcased potential for smart biofouling biomaterials with a hide-and-reveal capability.

Conclusions:

  • The described surface chemistry strategy offers a versatile platform for developing new switchable materials.
  • This approach facilitates noninvasive, in situ control over biomolecular interactions.
  • The findings open avenues for advanced smart biomaterials and real-time cell behavior studies.