Related Experiment Video
Updated: Jun 1, 2026

07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Rubella-related intermediate uveitis in pregnancy--a rare presentation
Annamalai Thirupathy1, Iqbal Tajunisah
1Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Ocular Immunology and Inflammation
|May 21, 2011
Summary
This case report highlights a rare instance of intermediate uveitis in a pregnant woman due to rubella infection. Early recognition and treatment led to vision improvement and a healthy fetus.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Maternal-Fetal Medicine
Background:
- Rubella infection during pregnancy can lead to various complications.
- Intermediate uveitis is an inflammatory eye condition affecting the vitreous and ciliary body.
- Ocular manifestations of maternal infections require careful consideration.
Observation:
- A 35-year-old pregnant woman presented with acute vision blurring and floaters in her left eye at 24 weeks gestation.
- Ocular examination revealed vitritis without retinal involvement.
- High rubella IgG titers confirmed recent infection.
Findings:
- Treatment with periocular corticosteroids resulted in significant visual improvement and resolution of vitritis within 3 weeks.
- Rubella IgG titers decreased substantially post-treatment.
- Fetal well-being was unaffected, confirmed by obstetric evaluation.
Implications:
- Rubella-associated intermediate uveitis is an uncommon but treatable complication during pregnancy.
- Prompt investigation for rubella is crucial in pregnant patients with unexplained visual disturbances.
- Early diagnosis and management can prevent severe ocular complications and ensure a positive maternal-fetal outcome.
Related Concept Videos
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Development of Immunocompetence
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Rh Blood Group
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.

