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Updated: Jun 1, 2026

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Cervical thymic cysts in adults.

Nikolaos Michalopoulos1, Theodossis S Papavramidis, Georgia Karayannopoulou

  • 13rd Department of Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. nickos.michalopoulos@gmail.com

Thyroid : Official Journal of the American Thyroid Association
|May 21, 2011
PubMed
Summary

Cervical thymic cysts (CTCs) are rare adult neck masses, often asymptomatic and misdiagnosed. Surgical excision is the treatment of choice for these benign lesions.

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Area of Science:

  • Head and Neck Surgery
  • Endocrinology
  • Pathology

Background:

  • Cervical thymic anomalies include ectopia, cysts, and thymomas.
  • Cervical thymic cysts (CTCs) are rare benign neck masses in adults, with prevalence less than 1% of cervical masses.
  • CTCs are typically diagnosed in childhood but can present in adults, often missed preoperatively.

Observation:

  • A systematic literature review identified 36 adult patients with CTCs.
  • The mean age of affected patients was 36 years, with a male/female ratio of 4/5.
  • Most CTCs were asymptomatic and diagnosed post-surgery via pathology.

Findings:

  • In most cases, thymic cysts were not included in the preoperative differential diagnosis.
  • Surgery is the recommended treatment, requiring careful preoperative assessment of cyst size, location, and relation to vital neck structures.
  • Surgical excision, often via a transverse cervical incision, can be challenging due to the proximity of CTCs to the carotid sheath and major nerves.

Implications:

  • CTCs are uncommon causes of neck swelling and frequently misdiagnosed preoperatively.
  • Surgical excision followed by histological examination confirms the diagnosis.
  • Cervical thymic cysts should be considered in the differential diagnosis of cervical cystic masses in adults.