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Updated: Jun 1, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
Published on: November 7, 2020
[Association between the use of blood components and the five-year mortality after liver transplant]
Bruno Salomé de Morais1, Marcelo Dias Sanches, Daniel Dias Ribeiro
1SBA Organ Transplant Commitee, Anesthesiologist of the Grupo de Transplante of Instituto Alfa de Gastroenterologia/UFMG and Hospital Lifecenter. brunomoraisanest@yahoo.com.br
Background And Objectives:
Liver transplant (LT) surgery is associated with significant bleeding in 20% of cases, and several authors have demonstrated the risks related to blood components. The objective of the present study was to evaluate the impact of using blood components during hospitalization in five-year survival of patients undergoing LT.
Methods:
One hundred and thirteen patients were evaluated retrospectively. Several variables, including the use of blood components intraoperatively and throughout hospitalization, were categorized and evaluated by univariate analysis using Fisher's test. A level of significance of 5% was adopted. Results with p < 0.2 underwent multivariate analysis using multinomial logistic regression.
Results:
Parenchymal diseases, preoperative renal dysfunction, and longer stay in hospital and ICU are associated with greater five-year mortality after LT (p < 0.05). Unlike the intraoperative use of blood components, the accumulated transfusion of packed red blood cell, frozen fresh plasma, and platelets during the entire hospitalization was associated with greater five-year mortality after liver transplantation (p < 0.01).
Conclusions:
This study emphasizes the relationship between the use of blood components during hospitalization and increased mortality in five years after LT.
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