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Updated: Jun 1, 2026

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
Published on: October 7, 2025
Stay tuned: miRNA expression and nonsense-mediated decay in brain development
1Department of Pediatric Oncology, University of Heidelberg and Molecular Medicine Partnership Unit of the European Molecular Biology Laboratory and the University of Heidelberg Medical Faculty, Im Neuenheimer Feld 430, D-69120 Heidelberg, Germany. andreas.kulozik@med.uni-heidelberg.de
Abstract:
In this issue of Molecular Cell (Bruno et al., 2011), regulation of the key nonsense-mediated RNA decay (NMD) proteins UPF1 and MNL51 (BTZ) by miRNA 128 is discovered to fine-tune gene expression in brain differentiation, thus documenting a novel cooperation of two posttranscriptional mechanisms of gene regulation in developmental decision making.
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Nonsense-mediated mRNA Decay
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