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Updated: Jun 1, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
[Papillomavirus and head and neck cancer]
G Lescaille1, V Descroix, J Azérad
1Service d'odontologie, UFR d'odontologie université Paris Diderot, groupe hospitalier Pitié-Salpêtrière, 43-87 boulevard de l'hôpital, Paris. France. Geraldine.lescaille@gmail.com
Abstract:
Tobacco and alcohol consumption are the main risk factors for head and neck cancers. Papillomavirus (HPV) infection was recently associated with the development of malignant tumors of the oropharynx, according to molecular and biological arguments. We describe the oncogenic mechanisms of HPV infections, the epidemiological and clinical aspects of associated head and neck cancers, their prognosis, and issues of specific therapeutic strategies.
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