Related Experiment Video
Updated: Jun 1, 2026

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
Published on: June 28, 2018
Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature
Fabrice Roux1, Maria Colomé-Tatché, Cécile Edelist
1Laboratoire Génétique et Evolution des Populations Végétales, Centre National de la Recherche Scientifique 3268, Université des Sciences et Technologies de Lille 1, 59655 Villeneuve d'Ascq, France.
Abstract:
We extensively phenotyped 6000 Arabidopsis plants with experimentally perturbed DNA methylomes as well as a diverse panel of natural accessions in a common garden. We found that alterations in DNA methylation not only caused heritable phenotypic diversity but also produced heritability patterns closely resembling those of the natural accessions. Our findings indicate that epigenetically induced and naturally occurring variation in complex traits share part of their polygenic architecture and may offer complementary adaptation routes in ecological settings.
Related Concept Videos
Epigenetic Regulation
X-chromosome...
Epigenetic Regulation
Epigenetic Regulation
Mutation, Gene Flow, and Genetic Drift
Gene-Environment Interactions
Mutations in Microorganisms

