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Updated: Aug 13, 2026

Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions
Published on: October 13, 2015
In vitro effect of YTR (tazobactam) on plasmid and chromosomally mediated beta-lactamases
1Department of Medical Microbiology, State University of Limburg, Maastricht, The Netherlands.
Abstract:
The effect of tazobactam on the piperacillin susceptibility and on the beta-lactamase activity of different strains and species was evaluated. A synergistic effect was observed on the piperacillin susceptibility for all microorganisms tested, irrespective of the type and/or amount of beta-lactamase produced. Addition of gentamicin resulted in a further reduction of the piperacillin MIC. The enzyme activity after induction with piperacillin alone or in combination with tazobactam (4 mg/l) was quite similar.
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