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Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Updated: Jun 1, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Glaucoma following infantile cataract surgery.

Robert M Saltzmann¹, David R Weakley, Nalini K Aggarwal

¹University of Texas Southwestern Medical Center, Dallas, TX 75390-9057, USA.

Journal of Pediatric Ophthalmology and Strabismus

|May 24, 2011

Summary

Infantile cataract surgery can lead to secondary glaucoma, especially in infants under 3 months. Most affected eyes require surgery, and visual outcomes remain poor, highlighting ongoing risks.

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Last Updated: Jun 1, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Area of Science:

Ophthalmology
Pediatric Ophthalmology

Background:

Infantile cataracts require surgical intervention.
Secondary glaucoma is a known complication of cataract surgery.

Purpose of the Study:

To determine the incidence, risk factors, and outcomes of glaucoma after infantile cataract extraction.
To identify specific patient and surgical factors associated with glaucoma development.

Main Methods:

Retrospective chart review of pediatric patients undergoing cataract extraction.
Inclusion criteria: cataract extraction between January 1, 1993, and December 31, 2006.
Statistical analysis to identify risk factors for glaucoma development.

Main Results:

17.2% of eyes developed glaucoma post-surgery.
Younger age at diagnosis (<3 months) and anterior chamber anomalies were significant risk factors.
72.2% of glaucoma cases required surgical intervention; 30% had poor visual acuity (<20/400).

Conclusions:

Infantile cataract surgery carries a significant risk of secondary glaucoma.
Early diagnosis and extraction (<3 months) increase glaucoma risk.
Glaucoma following infantile cataract surgery often necessitates intervention and is associated with poor visual outcomes.