Role for purinergic receptors in memory processing in young chicks
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Updated: Jun 1, 2026

Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis
Published on: August 20, 2020
Catherine Cronin1, Thomas M Edwards, Marie E Gibbs
1School of Psychology & Psychiatry, Monash University, Clayton, 3800 Victoria, Australia. ccronin@swin.edu.au
Abstract:
The current study used a single trial bead discrimination task for the young chick to ascertain if inhibitors of P2 purinergic receptors would impair memory retention. Suramin and PPADS provided similar retention profiles. Loss of memory retention was evident by 60 min post-training. Both drugs caused persistent memory loss which was still evident 24h post-training. These findings suggest that P2 receptors have a role in memory processing.
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