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Updated: Jun 1, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Update on pediatric sleep-disordered breathing
Manisha Witmans1, Rochelle Young
1Division of Pediatric Respiratory Medicine, University of Alberta, Edmonton, AB, Canada. manisha.witmans@albertahealthservices.ca
Insights
Pediatric sleep-disordered breathing (SDB), including obstructive sleep apnea, is common but underdiagnosed. It significantly impacts children's health, affecting multiple organ systems, and presents diagnostic and treatment challenges.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Child Health Research
Background:
- Sleep-disordered breathing (SDB) is a prevalent condition in children.
- Obstructive sleep apnea is the most common and significant form of pediatric SDB.
- Pediatric SDB is frequently underdiagnosed despite its high prevalence.
Purpose of the Study:
- To review recent advancements in understanding pediatric SDB.
- To highlight the significant end-organ dysfunction associated with pediatric SDB.
- To discuss current challenges in diagnosing and treating pediatric SDB.
Main Methods:
- Literature review of recent studies on pediatric SDB.
- Synthesis of current knowledge on SDB pathophysiology and consequences.
- Analysis of diagnostic and therapeutic challenges in pediatric populations.
Main Results:
- Pediatric SDB encompasses a spectrum of respiratory disorders, with obstructive sleep apnea being most common.
- SDB is associated with substantial cardiovascular, neurocognitive, and metabolic end-organ damage in children.
- Significant challenges persist in the diagnosis and management of pediatric SDB.
Conclusions:
- Pediatric SDB, particularly obstructive sleep apnea, requires greater clinical attention due to its prevalence and health impacts.
- Understanding the multifaceted consequences of SDB is crucial for effective intervention.
- Addressing diagnostic and treatment barriers is essential for improving outcomes in children with SDB.
Abstract:
Pediatric sleep-disordered breathing (SDB) includes an increasingly recognized, highly prevalent, yet still underdiagnosed spectrum of respiratory disorders, the most common and clinically significant of which is obstructive sleep apnea. SDB is linked with significant end-organ dysfunction across various systems, particularly with cardiovascular, neurocognitive, and metabolic consequences. This review summarizes recent advances in understanding of pediatric SDB and discusses the challenges inherent in diagnosing and treating children with SDB.
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