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Updated: Feb 10, 2026

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
Published on: January 13, 2022
Nerve problems in the lower extremity
Wilson Z Ray1, Susan E Mackinnon
1Department of Neurological Surgery, Washington University School of Medicine, St Louis, MO 63110, USA.
Abstract:
The article provides an overview of management and repair strategies for lower extremity peripheral nerve injuries. It discusses the indications for autografts, nerve conduits, allografts, end-to-side repairs, primary repair, and nerve transfers. The relative pros and cons of each strategy are discussed, providing a broad overview of treatment options for the management of lower extremity nerve injuries.
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