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Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

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Related Experiment Video

Updated: Jun 1, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
05:06

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Diabetic peripheral neuropathy.

Michael S Pinzur1

  • 1Department of Orthopaedic Surgery, Loyola University Health System, Maywood, IL 60153, USA. mpinzu1@lumc.edu

Foot and Ankle Clinics
|May 24, 2011
PubMed
Summary
This summary is machine-generated.

Diabetic peripheral neuropathy is common in adults with diabetes and requires early recognition. Prompt preventive strategies can reduce risks of serious foot complications like ulcers and amputations.

Related Experiment Videos

Last Updated: Jun 1, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
05:06

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Area of Science:

  • Neurology
  • Endocrinology
  • Diabetology

Background:

  • Diabetic peripheral neuropathy affects up to one-third of adults with diabetes.
  • It is a common complication, with nearly all diabetic patients likely to develop it over time.
  • Early identification is vital for implementing preventive measures.

Purpose of the Study:

  • To highlight the prevalence and significance of diabetic peripheral neuropathy.
  • To emphasize the importance of early diagnosis for preventing severe foot complications.
  • To review current treatment approaches and their limitations.

Main Methods:

  • Literature review on diabetic peripheral neuropathy prevalence and impact.
  • Analysis of current treatment strategies, including glucose control and pharmacotherapy.
  • Evaluation of alternative treatment modalities.

Main Results:

  • Diabetic peripheral neuropathy is highly prevalent and poses significant risks.
  • Optimal glucose and hemoglobin A1C control remain the primary treatment.
  • Pharmacological treatments for pain are limited in efficacy.
  • Alternative therapies have shown minimal success to date.

Conclusions:

  • Early recognition of diabetic peripheral neuropathy is crucial for preventing debilitating foot conditions.
  • Effective management relies heavily on glycemic control.
  • Current therapeutic options for pain and alternative treatments offer limited benefits.