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Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Evidence that the mismatch negativity to pattern violations does not vary with deviant probability.

Lauren D Sculthorpe¹, Kenneth B Campbell

¹National Research Council Institute for Biodiagnostics (Atlantic), Halifax, Nova Scotia, Canada. lauren.sculthorpe@nrc-cnrc.ca

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology

|May 24, 2011

Summary

The mismatch negativity (MMN) amplitude did not consistently decrease with increasing deviant probability in auditory pattern violations. This suggests that once a stable memory representation is formed, further regularity examples may not strengthen it.

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Dissociation of the Confounding Influences of Expectancy and Integrative Difficulty Residing in Anomalous Sentences in Event-related Potential Studies

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Area of Science:

Auditory Neuroscience
Cognitive Psychology
Event-Related Potentials

Background:

The mismatch negativity (MMN) is an event-related potential reflecting automatic change detection in auditory processing.
A classic finding is the inverse relationship between MMN amplitude and the probability of deviant stimuli.
This relationship's applicability to violations of concrete rule patterns requires further investigation.

Purpose of the Study:

To investigate if the inverse relationship between MMN amplitude and deviant probability holds for violations of concrete auditory rule patterns.
To explore the influence of deviant probability on MMN amplitude in patterned auditory sequences.

Main Methods:

Three experiments were conducted using auditory sequences with varying deviant probabilities.
Experiment 1 presented oddball and patterned sequences at high (0.16) and rare (0.02) deviant probabilities.
Experiments 2 and 3 employed different patterns and probability levels (0.08, 0.04) and included active detection tasks.

Main Results:

Experiment 1 showed an inverse relationship between MMN amplitude and deviant probability.
However, Experiment 2 found no such effect of probability on MMN amplitude.
Experiment 3 indicated that high deviant probability might destabilize memory representations of auditory patterns.

Conclusions:

The amplitude of the MMN to violations of concrete auditory patterns does not consistently vary with deviant probability.
A stable memory representation of auditory sequence regularities may not be further strengthened by additional examples.