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Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
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Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
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Nose and Nasal Cavity

The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Primary sinonasal meningioma.

M Mnejja1, B Hammami, L Bougacha

  • 1Service ORL et chirurgie cervico-faciale, CHU Habib-Bourguiba, Sfax, Tunisia. mnejjamalek@gmail.com

European Annals of Otorhinolaryngology, Head and Neck Diseases
|May 24, 2011
PubMed
Summary
This summary is machine-generated.

Primary sinonasal meningiomas are rare tumors that are difficult to diagnose. Histological examination is crucial for accurate diagnosis, and complete surgical resection offers an excellent prognosis.

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Area of Science:

  • Neuro-oncology
  • Head and Neck Pathology
  • Surgical Oncology

Background:

  • Primary meningiomas of the sinonasal tract are rare and challenging to diagnose preoperatively.
  • Ectopic meningiomas in this location present with non-specific symptoms, complicating early identification.
  • Accurate diagnosis relies heavily on histological and immunohistochemical analysis.

Observation:

  • A case of a seventeen-year-old female presenting with unilateral nasal obstruction over one year.
  • Initial imaging revealed a sinonasal mass, and biopsy suggested inverted papilloma.
  • Endoscopic resection was performed, with final pathology confirming a meningothelial meningioma.

Findings:

  • The final diagnosis of sinonasal meningioma was established post-operatively through histopathology.
  • Immunohistochemistry aids in differentiating meningiomas from other sinonasal tumors.
  • Imaging plays a role in confirming the tumor's sinonasal origin.

Implications:

  • Complete surgical extirpation is the primary treatment for sinonasal meningiomas.
  • Adjuvant therapy is generally not required following complete resection.
  • Early and accurate diagnosis, though challenging, leads to favorable patient outcomes.