Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Antidepressant Drugs: Overview01:25

Antidepressant Drugs: Overview

Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring Inflation-Related Public Discourse Relevant to Social Determinants of Health Using Social Media Data.

International journal of environmental research and public health·2026
Same author

Interpretable machine learning for rare events: an inverse probability weighted application to understanding glucagon-like peptide-1 receptor agonists use and incident alcohol-related disorder.

Alcohol and alcoholism (Oxford, Oxfordshire)·2026
Same author

AI-Driven Speech Analysis for Mental Health Prediction in Individuals with Voice Disorders.

Journal of voice : official journal of the Voice Foundation·2026
Same author

Accuracy of diagnostic codes to identify metastatic prostate cancer in medicare claims database.

Cancer epidemiology·2026
Same author

Predicting Anticipated Telehealth Use: Development of the CONTEST Score and Machine Learning Models Using a National U.S. Survey.

Healthcare (Basel, Switzerland)·2026
Same author

Association of Combined Marijuana and Opioid Use with Major Depressive Disorder Among Adults with Chronic Conditions in the United States.

Substance use : research and treatment·2026

Related Experiment Video

Updated: Jun 1, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

Multimorbidity and depression treatment.

Ami Vyas1, Usha Sambamoorthi

  • 1Department of Pharmaceutical Systems & Policy, School of Pharmacy, West Virginia University, Morgantown, WV 26506-9510, USA. avyas@hsc.wvu.edu

General Hospital Psychiatry
|May 24, 2011
PubMed
Summary

Individuals with multiple chronic physical conditions receive depression treatment at rates similar to those with a single condition. Increased healthcare system contact may explain this finding for depression care.

More Related Videos

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Related Experiment Videos

Last Updated: Jun 1, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Area of Science:

  • Health Services Research
  • Chronic Disease Management
  • Mental Health Treatment

Background:

  • Depression is a common comorbidity with chronic physical conditions.
  • Understanding depression treatment disparities in patients with multiple chronic conditions is crucial for equitable care.

Purpose of the Study:

  • To compare depression treatment utilization among adults with multiple versus single chronic physical conditions.
  • To identify factors influencing depression treatment access and adherence in complex patient populations.

Main Methods:

  • Cross-sectional study of 1,376 adults with depression and at least one chronic condition.
  • Analysis of data from the 2007 Medical Expenditure Panel Survey.
  • Controlled for demographic, socioeconomic, access to care, and outpatient visit variables.

Main Results:

  • 56.2% used antidepressants, 21.4% received psychotherapy, and 22.5% reported no depression treatment.
  • No statistically significant differences in depression treatment type were observed between individuals with multiple versus single chronic conditions after adjustment.
  • Factors controlled for included demographics, socioeconomic status, and healthcare access.

Conclusions:

  • Individuals with multiple chronic conditions appear to receive depression treatment at similar rates to those with single conditions.
  • Increased healthcare system engagement may facilitate comparable depression treatment access.
  • Competing demands from multiple chronic conditions may not impede depression treatment seeking or receipt.